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The team found that the variant with the dianionic linker (i.e., [ 64 Cu]Cu-NOTA-AHDA-RM26) boasted a significantly reduced binding affinity for GRPR (18.0 ± 2.8 nM) compared to the PEG- and piperazine-bearing probes (1.0 ± 0.5 and 1.0 ± 2.0 nM, respectively)
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