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1,15 Hyperglycemia-induced metabolic pathways Polyol pathway activation In a hyperglycemic state, excess glucose is shunted into the polyol pathway, where aldose reductase catalyzes its reduction to sorbitol, which in turn is oxidized to fructose by sorbitol dehydrogenase
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If you develop diarrhoea after starting B12 supplementation, it is worth considering other factors that may be contributing to your symptoms
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