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TUG1–miR-148b–IGF-2 The lncRNA TUG1 (taurine up-regulated gene 1) is believed to act in cardiovascular disease by enhancing atherosclerosis in part through an increase in vascular smooth muscle cell (VSMC) proliferation and survival [78]
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Because [ 11 C]-radiolabeled metabolites of loperamide could also be formed in the non-human primate, the magnitude of P-gp inhibition in the monkey may be underestimated by the non-P-gp substrate metabolites
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