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In the plasma, NAC undergoes redox exchange reactions with L-cystine, to generate plasma LC at a concentration capable of achieving the maximal rate of GSH synthesis in erythrocytes [69] and LC/NAC increase the rate of GSH biosynthesis in erythrocytes in vitro [70]
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One factor affecting the metabolism of APAP is the presence of autoantibodies that impair folate transport to the brain, which is found in almost 3 quarters of children with ASD [70]
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