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Pentanethiol was used as a filler to ensure sufficient interspacing between Apts, so that the individual IFNฮณ proteins could bind to the Apt without hindrance
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In parallel, ferroptosis suppressor protein 1 (FSP1)/ubiquinol (CoQH2), dihydroorotate dehydrogenase/CoQH2 and GTP cyclohydrolase 1 (GCH1)/tetrahydrobiopterin have been identified as independent systems that scavenge free radicals to exert their antioxidative effects and suppress ferroptosis (17-21)
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