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Research shows that, the progression from simple hepatic steatosis to nonalcoholic steatohepatitis (NASH) involves significant mitochondrial dysfunction [211]
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[1] Because intrinsic-factor-dependent uptake in the distal ileum can be absent in conditions such as autoimmune gastritis, pancreatic insufficiency, or bariatric surgery, the intramuscular or subcutaneous route bypasses gastrointestinal barriers and reliably restores serum concentrations
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