glutathione peroxidase-1 overexpression overexpressing transgenic mice are protected from cocaine-induced drug dependence Glutalight Glycerin Soap |

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Results GSH depletion induces cell death in RPE cells To evaluate the effect of GSH depletion on the RPE cells, we used three different approaches: depletion of Cys 2 from cell culture media, treatment with buthionine sulphoximine (BSO, 1000 µM) to block de novo synthesis of GSH, or treatment with erastin (10 µM), an inhibitor of system x c − 1

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