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demonstrated that phosphorylation of threonine 522 of SIRT1 is crucial for tissue-specific regulation of SIRT1 activity, activation of hepatic SIRT1 in response to excess caloric intake, and a threonine 522 dephosphorylation mimic impairs energy metabolism (87)
N-Acetyl Cysteine
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Eur.) according to European Arzeneibbuch and an isotonic saline solution (0.9%)
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