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This review provides a comprehensive overview of the current state of knowledge on antidepressant bioactivation, the metabolizing enzymes responsible for reactive metabolite formation, and their potential implication in hepatotoxicity
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Size:130g
Moreover, we also reproduced the reaction of SnCE1 with SUMO1-PA and SUMO3-PA probes with higher efficiency towards SUMO1-PA compared to SUMO3-PA and its efficient deSUMOylase activity cleaving polymeric SUMO2 [2–6] chains to yield mono-SUMO2 (Fig
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