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These research findings underscore the importance of histone modifications in tumor immune evasion and imply that aiming at histone modifications may be a promising new approach to overcome resistance to immunotherapy

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On the other hand, Byrne and colleagues examined the impact of increased colonic propionate production on brain anticipatory reward responses during the examination of food images, hypothesizing that increased propionate would reduce both reward responses and ad libitum calorie intake by promoting the release of anorexigenic gut hormones 69