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Developing effective treatments for CNS disorders requires an understanding of NF-κB processes and effects ( 4.4 PTGS2/COX-2: an important link between ferroptosis and neuroinflammation in the pathophysiology of the central nervous system Cyclooxygenase-2 (COX-2) or prostaglandin-endoperoxide synthase 2 (PTGS2) is an enzyme that can be produced in response to specific circumstances (Jaén et al., 2018)
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