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List of Abbreviation ΔΨm Mitochondrial membrane potential 6-OHDA 6-hydroxydopamine BBB Blood-brain barrier CAT Catalse CGNs Cerebellar granular neurons CREB cAMP responsive element-binding protein (CREB) IPQ Imidazole pyrroloquinoline LDH Lactate dehydrogenase MMP Matrix metalloproteinase MTFA Mitochondrial transcription factor A NGF Nerve growth factor NMDA N-methyl-D-aspartate NO Nitric oxide NRF-1 Nuclear respiratory factor 1 NRF-2 Nuclear respiratory factor 2 PASMCs Pulmonary artery smooth muscle cells PGC-1α Peroxisome proliferator-activated receptor-γ coactivator-1α PH Pulmonary hypertension Pyrroloquinoline Quinone PQQC Pyrroloquinoline quinone synthase C ROS Reactive oxygen species SOD Superoxide dismutase TBARS Thiobarbituric acid reacting substances TBI Traumatic brain injury Data availability No data was used for the research described in the article