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The rate limiting enzymes glucose-6-phosphatase (G6PC), FBP1 and phosphoenolpyruvate carboxykinase 1 (PCK1) are all decreased in ccRCC and are associated with reduced overall survival 143, 144, 145
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[DOI] [PubMed] [Google Scholar] Spencer J.P.E., Whiteman M., Jenner P., Halliwell B
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