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Frontiers | Hepatotoxicity induced by arsenic trioxide: clinical features, mechanisms, preventive and potential therapeutic strategies
The four amino-acid substitutions relative to native GHRH(1-29) are engineered to resist that enzymatic degradation — particularly cleavage by dipeptidyl peptidase-4 (DPP-4) at the N-terminus — which extends the peptide’s functional plasma half-life modestly relative to unmodified sermorelin-type fragments
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Vitamin C boosts DNA demethylation in TET2 germline mutation carriers
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