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2 As an essential redox carrier, NAD + receives hydride from metabolic processes including glycolysis, the TCA cycle, and fatty acid oxidation (FAO) to form NADH
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It should be noted that a dichotomous outcome, such as the proportion of patients who were relapse-free (the outcome used in the analysis of Munari and colleagues) instead of relapse rate (used by Martinelli Boneschi and colleagues), is a more sensitive outcome measure (70
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