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17a,b), the presence of inactive Pd/C results in an increase of direct oxidation selectivity by 49%
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This is achieved by recruitment of mTORC1 to the lysosomal membrane by GTP-bound RagA/B and GDP-bound RagC/D (activated by cytosolic amino acid sensors and lysosomal cholesterol sensors), and activation of mTORC1 on the lysosomal membrane by GTP-bound Rheb (activated by growth factors)
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