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The effective suppression of metHb formation seems to be an important mechanism for maintaining health over time and successful aging (56)

In Vitro Research

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Comparison between two truncated MOR in the C terminal tail in HEK cells over-expressing a GRK2 peptide known to block G βγ -mediated recruitment of GRK at the plasma membrane suggest that the amino acids sequence 354TSST357 plays a major role in GRK2-mediated MOR desensitization upon DAMGO exposure (Wang, 2000)

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