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The oral formulation is the most significant differentiator: if an oral tablet can produce weight loss comparable to injectable CagriSema, it could fundamentally change how dual pathway obesity therapy is delivered
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Excess copper enters via CTR1, and excess ROS reduces GSH and drives OX-LDL production, contributing to atherosclerosis, Drp1-mediated fission, mPTP opening, and ultimately cuproptosis
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