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On the other hand, a study in vitro explored the effect of EGT on rat vascular reactivity, and it was concluded that EGT could protect nitric oxide from damage and maintain its activity by reducing superoxide anions (Gokce and Arun, 2014)
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The 50–100mg daily dose range was derived from rodent models where 10mg/kg bodyweight produced measurable NNMT suppression without toxicity across 12-week administration periods
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