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87 Gastrodin, a phenolic glycoside isolated from the dried rhizomes of Gastrodia elata Blume [Orchidaceae], inhibits ferroptosis by modulating the PI3K/Akt/Alkbh5 axis to upregulate Gclm via m6A demethylation, while concurrently modulating the xCT/GPX4 and ACSL4/LPCAT3 pathways, as evidenced by decreased MDA and increased SOD/GSH levels
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