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In the case of the central nervous system (CNS), chronic HHcy (250 mg/kg body weight for 60 days) in mice was associated with increased activity of the cytosolic form of superoxide dismutase (Cu/ZnSOD) and catalase in the nucleus of the caudate shell and black nucleus
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This includes the standard fertility treatment corifollitropin alfa, tested in Phase III, and two monoclonal antibodies in preclinical phases: HAT 002, and the anti-CD19 antibody (aCD19 Ab)
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