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characterization of whether effects are additive or potentiating in tendon, muscle, and skin healing models Angiogenesis (BPC-157 axis) — tube formation assays, vascularization models, measurements of VEGF/VEGFR2 expression and FAK-paxillin complex activity in endothelial cell cultures Cell migration and cytoskeleton dynamics (Tβ4 axis) — migration tests (scratch assay, transwell), imaging of F-actin dynamics, measurements of the effect on G-actin sequestration in cultures of fibroblasts, keratinocytes and endothelial cells Models of connective tissue reparation — animal models of tendon, muscle and skin damage