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Glucose-6-phosphate dehydrogenase also an essential role in this system by sustaining NADPH production, a critical cofactor for GSH regeneration and other reductive reactions [3]
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Nonetheless, the inability of OPCs to differentiate into mature oligodendrocytes in the aged brain is not currently debated, and it likely contributes to the reduced capacity for remyelination and declining oligodendrocyte population (Sim et al., 2002
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