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Effects of N-acetylcysteine on sciatic nerve healing: A histopathological, functional, and biochemical study of the rat sciatic nerve - PMC
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Specifically, circulating LPS binds to TLR4 on immune cell surfaces, activating the downstream NF-κB signaling pathway and promoting the release of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), and interleukin-1 beta (IL-1β)
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