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The effects of the oral supplementation of L‐Cystine associated with reduced L‐Glutathione‐GSH on human skin pigmentation: a randomized, double‐blinded, benchmark‐ and placebo‐controlled clinical trial - Duperray - 2022 - Journal of Cosmetic
Under pathological conditions, the permeability transition pores continue to open under the stimulation of oxygen free radicals or Ca 2+ , resulting in mitochondrial swelling, the release of Cyt-c, and consequently caspase-3 activation, resulting in a series of mitochondria-mediated apoptotic cascade responses (Eloy et al., 2012)
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