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Although cholesterol is essential for certain cell functions, there may be a role for atorvastatin in preventing some dementias (especially in patients with certain metabolic syndromes or with ApoE4 mutations), with possible reduction of β-amyloid production, reduction of vascular inflammation, protection of endothelial cell function and reduction of brain ischemia (67)
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Furthermore, several studies have confirmed Gα s in complex with all three receptors following agonist binding [49,66]
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