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A more holistic approach—potentially incorporating topically applied combinations of agents aimed at protecting peripheral nociceptive endings (nociceuticals) - may serve as a valuable adjunct during and after treatment, providing supportive care for patients with neuropathy while new therapies are developed or personalized cancer treatments help reduce CIPN incidence
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These findings have important clinical implications, as they suggest that GLP-1 analogs could be a viable treatment option for patients with MSH, PSW, or other forms of obesity resulting from MC4R deficiencies
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