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The aglycone moiety of the substrate makes non-polar contacts with loops 5 and 6, and the two α2-helix loops extended from N-terminal domains of the two adjacent subunits (shown as A and B subunits in Supplementary Fig

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For the differential cell count, 100 µL of the cell button was resuspended and cytocentrifuged at 300 xg for 10 min at 4 °C to produce slides stained by the Diff-Quick technique, using hemocytological criteria