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Following this treatment, the microbiological shelf life of meat under refrigerated conditions increased to about 8 days, while in the control samples this period was shorter
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Using in silico design, structure–activity relationships (SARs), chemical optimization, cell-based assays and in vivo experiments, we identified and characterized the first-in-kind small-molecule inhibitors of STX7–Munc13-4-dependent endosomal maturation and signaling for use in immune cells that contribute to systemic inflammation
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