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5-Amino-1MQ reduces NNMT, improving fat function, inflammation, mitochondrial output, and muscle repair.[23][32] In adipocytes, it boosts NAD+ by preventing its wasteful methylation, leading to better glucose handling
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In 2018, a Biochemical Pharmacology study reported that membrane-permeable NNMT inhibitors given to obese mice cut white fat mass and body weight and shrank adipocytes [5]
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