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Given that ferroptosis involves non-apoptotic pathways culminating in compromised cell membrane integrity, it is hypothesized that ferroptosis significantly contributes to PA-induced cytotoxicity and may account for this apparent difference between assays measuring distinct cellular endpoints

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Acknowledgements This work was supported by the National Key R&D Program of China (2021YFB3801000), Regional Key Project of National Natural Science Foundation of China (U20A20385), National Natural Science Foundation of China (22222503), the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB36000000) and Overseas High-end Talents Introduction Program (G2022011023L)