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They found that the use of rectal ozone improved O 2 saturation, reduced O 2 supply, decreased inflammation biomarkers (fibrinogen, D-dimer, urea, LDH, CRP, and IL-6), and significantly improved radiological outcomes, when compared to the standard of care group (Fernández-Cuadros et al., 2021)
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Mitochondrial GSH redox, oxidative DNA damage and apoptosis Cellular DNA damage upon exposure to a wide range of environmental genotoxins, anti-cancer drugs or ROS can induce a cascade of events that result in either cell cycle arrest and DNA repair or in cell apoptosis if the damage is extensive [106]
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