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improved behavioral test performance at 24 and 72 hoursGut-brain axis review (2024)Mixed preclinical and limited human dataFavorable safety signals in preliminary human data, but efficacy data remain limitedCNS pharmacology review (2023)Preclinical modelsBroad effects observed in lab settings, but no established clinical benefit in humans Traumatic Brain Injury and Recovery One of the more frequently cited findings involves traumatic brain injury models in mice

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Vigorous clonic contractions of the muscle groups of the head and neck, trunk and limbs then occur becoming progressively less violent over 1 minute.’ 32,33 The exact underlying pathophysiology is not understood