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Glucose deprivation activates AMPK/FoxO3a by binding to FoxO3a and inhibiting SLC7A11 expression, thus preventing erastin-induced ferroptosis
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Specifically, path A is inactive because the energy barrier associated with direct dissociation of the methyl ligand is higher than the barrier of intersection between two different electronic states: a metal-to-ligand charge transfer state (MLCT), and a ligand field state (LF) along the Co−O coordinate of the S 1 PES
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