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Oxidative stress from B12 deficiency can damage sperm chromatin (a tightly packed form of DNA inside the sperm), which affects fertilization potential

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In vivo nitrate generation The amounts of excreted nitrate greatly exceed that of what is typically ingested (Khatri et al ., 2017), and levels found in the plasma are between 20 and 40 μM under fasting conditions (Khambata et al ., 2015), implicating endogenous production