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Metabolism – Introduction to the Principles of Veterinary Pharmacology

Some other uncommon side effects may also occur when used in combination with cisplatin include vomiting, constipation, neutropenia, leukopenia, thrombocytopenia, anemia, and stomatitis/pharyngitis Contraindications It is contraindicated in patients with a history of severe hypersensitivity reaction to pemetrexed or to any other ingredient used in the formulation Special Precautions Patients should receive oral folic acid and vitamin B injections before the start and during therapy to reduce treatment related hematologic and gastrointestinal toxicities

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Overview of Renal Acid-Base Balance The kidneys play a critical role in the regulation of overall acid-base balance that ensures the maintenance of blood pH at around 7.4