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What are alternatives to regular B12 injections for MTHFR gene mutation?
A potential explanation for the latter might be that mature oligodendrocytes are epigenetically silenced, as suggested by the work of Liu and colleagues 90
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Its major metabolite, 1-MNA, activates nuclear factor erythroid 2-related factor 2 (NRF2) and inhibits nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling, thereby protecting cells against oxidative damage and inflammation
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