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The differential metabolites of DFG are mainly involved in pathway of alanine, aspartate, and glutamate metabolism, which is the most important metabolic pathway as it related to the most of other metabolic pathways, followed by arginine and proline metabolism, arginine biosynthesis, glycine, serine and threonine metabolism, glyoxylate and dicarboxylate metabolism, purine metabolism and aminoacyl-tRNA biosynthesis

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In the 24 hours following a TBI, there is a significant decrease in the number of circulating T cells (132) which affects both CD4 + T helper cells and CD8 + cytotoxic T cells