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Types of Liver Enzymes and Their Function Pharmacist Neeraj Bharti Innovator Academy Innovator Pharmacy Size:Small https://i.ytimg.com/vi/t4scKARrvmQ/mqdefault.jpg It is also possible that in active acromegaly, chronic exposure to elevated IGF-I levels resets IGF-IR responsiveness via the induction of IGF-IR resistance (70), as it has been demonstrated that prolonged stimulation with IGF-I induces functional IGF-IR resistance in vitro through the negative feedback loop (72) reduce stretch marks
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